Immunocal®

BERIKUT ADALAH PRESS RELEASE MANFAAT IMMUNOCAL TERHADAP AUTIS

2011-02-25T07:57:00.003+07:00

Haid Yang Sangat Menyiksa

2010-12-11T10:10:00.001+07:00

Varisesku Hilang, Betis Mulus Kembali

2010-12-11T10:02:00.001+07:00

Kanker Payudara

2010-09-20T05:49:00.002+07:00

Alergi dan Maag Tidak Lagi Mengganggu

2010-09-20T05:47:00.001+07:00

Tubuh Sehat Dengan Immunocal

2010-09-19T13:37:00.002+07:00

Berkat Immunocal Paru-paru Mita Disembuhkan

2010-09-19T13:19:00.002+07:00

Terbebas dari KANKER PAYUDARA Stadium 3

2010-04-07T22:33:00.003+07:00

Jantung Anakku Kembali Normal

2010-04-07T21:36:00.006+07:00

Brosur Immunocal Platinum

2009-08-29T18:46:00.003+07:00

Brosur Immunocal

2009-08-29T18:35:00.004+07:00

Proses Pembuatan Immunocal

2009-08-09T23:13:00.002+07:00

Proses ini telah di patent kan dan hanya Immunotec Inc. yang memiliki teknologi tersebut.
Jelasnya silahkan klik pada gambar.

Glutathione (GSH) dan Peranannya pada Diabetes

2009-08-09T22:59:00.004+07:00

Liputan Seminar Kesehatan tentang peranan Glutathione pada penderita DM. Klik gambar untuk memperjelas.

IMMUNOCAL & KANKER, Dapatkah disembuhkan?

2009-08-09T22:50:00.003+07:00

Silahkan klik gambar artikel di bawah ini untuk lebih jelasnya.

Perbedaan Immunocal & Colostrum

2009-08-09T22:33:00.003+07:00

PATENTS

2009-08-08T22:39:00.003+07:00

Immunocal
70 International "Method of Use" Patents.
Before we look at the actual patents that have been registered for Immunocal, it is critically important to recognize a few factors that set our product apart from ANY OTHER NEUTRACEUTICAL on the market.

You can see that we make specific reference to the fact that the Immunocal Patents are "METHOD OF USE" Patents.
Since most of the population knows what a "PATENT" is, this does not have to be explained.
However, most of the population DOES NOT KNOW what a "Method of Use" Patent is. So, here is the difference;

Just about anything can be patented by anyone, for things like; a new invention, a new way to manufacture something or a new blend of ingredients, all for a particular product that someone has created. These are very good patents for protecting something, so that it cannot be legally reproduced by someone else.

"Method of Use" Patents on the other hand are normally restricted to drugs because they actually state a specific result which has been proven scientifically, with Medical Community Standards of Research needed before they can be registered.

This is what sets Immunotec Research and Immunocal apart from the rest of the products and companies.

This is what allows you to rest assured that you are consuming the BEST PRODUCT available for YOUR IMMUNE SYSTEM, guaranteeing YOU that by consuming Immunocal, you are increasing your critical intracellular glutathione.

North & South America

Argentina
Canada
Chile
Mexico
United States

Europe to Africa

Austria
Czech Republic
Denmark
Europe
Germany

Israel
Italy
Norway
South Africa
Spain
Sweden
United Kingdom

Asia - Australia & New Zealand

Australia
China
Japan
New Zealand
Singapore
South Korea
Taiwan

Please CLICK the country flag above to view our Patents
Note: the original patents and research were done in Canada and the USA. You will notice some countries have patented all, while others have chosen to be conservative and only patent either the; Anti-cancer, HIV treatment or Immune Response patents, with the exception of Singapore. More patents will come, we are just getting started internationally...

Immunotec Inc. congratulates Dr. Luc Montagnier for winning the 2008 Nobel Prize in Medicine for his 1984 discovery, with Françoise Barré–Sinoussi, of the Human Immunodeficiency Virus (HIV).

Drs. Montagnier and Barré-Sinoussi first understood that HIV “impaired the immune system because of massive virus replication and cell damage to lymphocytes.” Their seminal work set the stage for understanding the biology of the disease and current modalities of treatment. In addition, it led to development of methods of diagnosis and blood screening that has mitigated the spread of the disease.

Dr. Montagnier and his colleagues edited Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases, devoting an entire chapter to a paper co-authored by Immunotec founding scientist Dr. Gustavo Bounous, entitled;

Nutriceutical Modulation of Glutathione with a Humanized Native Milk Serum Protein Isolate, Immunocal: Application in AIDS and Cancer,

Click here to View Document

source : http://immunocal.md/immunocal.patents.html

Immunocal Clinical Trials

2009-08-08T22:28:00.001+07:00

Immunocal
The Clinical Trials and Historical Research for Immunocal.

Research began in 1978 at McGill University, Montreal, Canada.
f
Dr. Gustavo Bounous and his staff at the immunology department, discovered a natural food source that dramatically increased the levels of glutathione in animal tissues and organs.

After the original discovery of the effects of this whey protein supplement, back in 1978 and futher understanding that the whey must remain in it's undenatured, unheated, natural and delicate state, several clinical trials were conducted around the world to investigate the effects of this natural food source, which was eventually named Immunocal, on the immune systems of mammals, including real human studies.

Immunocal Research Articles - Completed Clinical Trials

Competition for glutathione precursors between the immune system and the skeletal muscle:
Pathogenesis of chronic fatigue syndrome
G. Bounous¹, J. Molson²
¹Former Professor, Department of Surgery, McGill University, and career investigation of the Medical Research Council of Canada
²1994 Quebec Cycling Champion, Road and Time Trial
Read the article

The use of a whey protein concentrate in the treatment of patients with metastatic carcinoma:
A phase I-II clinical study
Renee S. Kennedy¹, George P. Konok¹, Gustavo Bounous², Sylvain Baruchel³, Timothy D. G. Lee⁴
¹Department of Surgery, Dalhousie University, Halifax, Nova Scotia;
²Department of Surgery, McGill University, Montreal, Quebec;
³Department of Pediatrics and Oncology, McGill University, Montreal, Quebec;
⁴Department of Immunology and Microbiology, Dalhousie University, Halifax, Nova Scotia, Canada
Read the article

Whey proteins as a food supplement in HIV-seropositive individuals
Gustavo Bounous, Sylvain Baruchel, Julian Falutz, Phil Gold
Departments of Surgery and Medicine, The Montreal General Hospital and McGill University, Montreal, Quebec
Read the article

The biological activity of undenatured dietary whey proteins: role of glutathione
Gustavo Bounous, Phil Gold
Departments of Surgery and Medicine, The Montreal General Hospital Research Institute and McGill University, Montreal, Quebec
Read the article

Whey proteins in cancer prevention
G. Bounous¹, G. Batist², P. Gold³
The Montreal General Hospital and McGill University, Montreal, Quebec, Canada
¹Professor of Surgery, McGill University, and Career Investigator of The Medical Research Council of Canada
²Director, Experimental Therapeutics, Department of Oncology, McGill University
³Chairman, Department of Medicine, McGill University, and Physician-in-Chief, The Montreal General Hospital
Read the article

Dietary Milk Proteins Inhibit the Development of Dimethylhydrazine-Induced Malignancy
Robert Papenburg¹, Gustavo Bounous¹, David Fleiszer¹, Phil Gold²
Departments of Surgery¹ and Medicine², The Montreal General Hospital and McGill University, Montreal, Quebec, Canada
Read the article

THE INFLUENCE OF DIETARY WHEY PROTEIN ON TISSUE GLUTATHIONE AND THE DISEASES OF AGING
Gustavo Bounous, Francine Gervais, Victor Amer, Gerald Batist and Phil Gold
The Montreal General Hospital Research Institute and McGill University, Departments of Surgery and Medicine
Read the article

IMMUNOENHANCING PROPERTY OF DIETARY WHEY PROTEIN IN MICE: ROLE OF GLUTATHIONE
Gustavo Bounous, Gerald Batist, Phil Gold
The Montreal General Hospital and McGill University, Departments of Surgery and Medicine, Montreal, Quebec
Read the article

The Immunoenhancing Property of Dietary Whey Protein Concentrate
Gustavo Bounous, Patricia A. L. Kongshavn, and Phil Gold
The Montreal General Hospital Research Institute, Departments of Surgery, Physiology and Medicine, McGill University, Montreal, Quebec
Read the article

DIETARY WHEY PROTEIN INHIBITS THE DEVELOPMENT OF DIMETHYLHYDRAZINE INDUCED MALIGNANCY
Gustavo Bounous, Robert Patenburg, Patricia A. L. Kongshavn, Phil Gold, and David Fleiszer
Departments of Physiology and Medicine, Montreal General Hospital and McGill University
Read the article

Mechanism of Altered B-cell Response Induced by Changes in Dietary Protein Type in Mice
Gustavo Bounous, Nazih Shenouda, Patricia A. L. Kongshavn, and Dennis G. Osmond
Department of Surgery, Centre Hospitalier Universitaire, Sherbrooke, Quebec, Canada;
Department of Anatomy and Physiology, McGill University, Montreal, Quebec, Canada
Read the article

Differential Effect of Dietary Protein Type on the B-Cell and T-Cell Immune Response in Mice
Gustavo Bounous and Patricia A. L. Kongshavn
Centre Hospitalier Universitaire, Sherbrooke, Quebec, Canada
Montreal General Hospital Research Institute and Department of Physiology, McGill University, Montreal, Quebec, Canada
Read the article

Influence of Dietary Protein Type on the Immune System of Mice
Gustavo Bounous, Louise Letourneau and Patricia A. L. Kongshavn
Centre Hospitalier Universitaire, Sherbrooke, Quebec, Canada
Montreal General Hospital Research Institute and Department of Physiology, McGill University, Montreal, Quebec, Canada
Read the article

Changes in Biliary Secretory Immunoglobulins A in Mice Fed Whey Proteins
Costantino AM, Balzola F, Bounous G
Read the article

Place for an antioxidant therapy in human immunodeficiency virus (HIV) infection
S. Baruchel, G. Bounous, P. Gold
McGill University, Department of Pediatrics and Medicine, McGill AIDS Centre, Montreal, Quebec, Canada
Read the article

Influence of Dietary Proteins on the Immune System of Mice
Gustavo Bounous and Patricia A. L. Kongshavn
Centre Hospitalier Universitaire, Sherbrooke, Quebec, Canada
Montreal General Hospital Research Institute and Department of Physiology, McGill University, Montreal, Quebec, Canada
Read the article

Influence of Dietary Lactalbumin Hydrolysate on the Immune System of Mice and Resistance to Salmonellosis
Gustavo Bounous, Mary M. Stevenson, Patricia A. L. Kongshavn
Centre Hospitalier Universitaire, Sherbrooke, Quebec, Canada
Montreal General Hospital Research Institute and McGill University, Montreal, Quebec, Canada
Read the article

Effect of supplementation with a cysteine donor on muscular performance
L. C. Lands, V. L. Grey and A. A. Smountas
Division of Respiratory Medicine, Department of Pediatrics and Biochemistry,
McGill University Health Centre-Montreal Childrens Hospital, Montreal, Quebec, Canada
Read the article

Treatment of Obstructive Airway Disease With a Cysteine Donor Protein Supplement
Bryce Lothian, MD; Vijaylaxmi Grey, PhD; R. John Kimoff, MD; and Larry C. Lands, MD, PhD
Departments of Pediatrics, Biochemistry and Division of Respiratory Medicine, McGill University Health Centre-Montreal Childrens Hospital
Division of Respiratory Medicine, McGill University Health Centre-Royal Victoria Hospital, Montreal, Quebec, Canada
Read the article

TREATMENT OF CHRONIC HEPATITIS USING WHEY PROTEIN (NON-HEATED)
A. Watanabe, K. Higuchi, K. Okada, Y. Shimizu, Y. Kondo and H. Kohri
Third Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan and
Otsuka Pharmaceutical Factory, Inc., Nutrition Research Institute, Tokushima, Japan
Read the article

Whey Protein Concentrate (WPC) and Glutathione Modulation in Cancer Treatment
Gustavo Bounous
Research and Development Department, Immunotec Research Ltd., Vaudreuil-Dorion, Quebec, Canada
Read the article

Enhancing Effect of Patented Whey Protein Isolate (Immunocal) on Cytotoxicity of an Anticancer Drug
Wayne Y. Tsai, Wen-Huei Chang, Ching-Hsein Chen, and Fung-Jou Lu
Department of Biochemistry, College of Medicine National Taiwan University, Taipei, Taiwan, ROC.
Read the article

Nutriceutical Modulation of Glutathione with a Humanized Native Milk Serum Protein Isolate, Immunocal^TM: Application in AIDS and Cancer
Sylvain Baruchel, Ginette Viau, Rene Olivier, Gustavo Bounous, Mark A. Wainberg
McGill University-Montreal Children's Hospital Research Institute, Montreal General Hospital, Montreal, Quebec, Canada
Jewish General Hospital, Lady Davis Institute, Montreal, Quebec, Canada and Pasteur Institute, Paris, France
Read the article

The Antioxidant System
Gustavo Bounous and John H. Molson
Research and Development Department, Immunotec Research Ltd., Vaudreuil-Dorion, Quebec, Canada
Read the article

Milk whey protein decreases oxygen free radical production in a murine model of chronic iron-overload cardiomyopathy
Wally J Bartfay, RN, PhD; Matthew T Davis, BNSc MScN(C); Jennifer M Medves, RN PhD; Stan Lugowski, PhD
Faculty of Nursing, University of Windsor, Windsor, Ontario, Canada
Department of Biochemistry and Trace Elements Laboratories, University of Toronto, Toronto, Ontario, Canada
Read the article

source : http://immunocal.md/clinical_trials.html

Cysteine-Rich Protein Prevents Weight Loss in Lung Cancer Patients: A Promising Intervention Study

2008-05-17T23:30:00.004+07:00

In Medical News

Immunotec Inc. (TSX-V: IMM) announced the successful completion of a multi-center randomized, double blind clinical trial on cancer-related weight loss (cachexia) in lung cancer patients which was performed in collaboration with various Canadian clinical centers(x). The research concluded that patients treated with IMN 1207 showed significant increases in body weight (Tozer et al. Antioxidants & Redox Signaling (2008) 10:395-402). Immunotec also announced the initiation of a follow-up study to confirm the positive results.

The massive loss of body weight and muscle mass in advanced cancer patients is typically associated with psychological stress, financial burden and a decreased quality of life. Until now there have been no dietary interventions known to satisfactorily prevent this process.

Immunotec's new study included 66 patients with advanced lung cancer receiving state of the art chemotherapy or radiotherapy. The patients had already suffered significant involuntary weight-loss prior to treatment. During a six month treatment period the patients were given either casein, a protein supplement low in cysteine which is widely used in clinical nutrition ("placebo") or IMN 1207, a specially-prepared glutathione enhancing cysteine-rich whey protein isolate supplied by Immunotec Inc. The results showed that patients in the placebo group continued to lose weight whereas patients treated with IMN 1207 showed a significant increase in body weight. Incidentally, these patients also showed an increase in strength and quality of life parameters. This study showed for the first time that cancer-related weight loss (cachexia) can be prevented by a single source of protein. Dr. Gerald Batist, Chair, Department of Oncology, McGill University stated "Having been involved in the early mechanistic studies of the therapeutic use of whey proteins, I'm pleased to see this particular formulation being tested in the clinic. The data to date encourage additional and expanded clinical trials". Dr. Wulf Droge, Senior Vice-President Research & Development at Immunotec Inc. emphasized that the results of this first trial should be viewed with cautious optimism. A second trial has been initiated to confirm the results.

Among other questions, this clinical trial also addressed the controversy about antioxidant use in chemotherapy. Since radiotherapy and many types of chemotherapy work by raising levels of oxidative stress and free radical formation to destroy cancer cells, oncologists have voiced concern that treatment of the patient with antioxidants may "protect" the cancer from the toxic effects of the therapy. If this were the case, antioxidants could even be expected to shorten the life span of the patients. Immunotec's study now showed that this was clearly not the case with IMN 1207. Based on his earlier work at his laboratory at the National Cancer Research Center of Germany (DKFZ) in Heidelberg, Dr. Droge was reasonably confident that supplementation with a critical precursor of the major cellular antioxidant glutathione, would actually improve the condition of the patients, most probably by ameliorating adverse effects of these therapies on the patients' healthy tissues. The results of this new study suggest that this is true. The antioxidant glutathione is distinct from other antioxidants including the popular antioxidant vitamins A, C, and E which are widely used as nutritional supplements. Glutathione is involved in the removal of reactive oxygen species and other potential toxic compounds through special biochemical processes and can reach relatively high and beneficial concentrations in cells and tissues depending on the availability of its biosynthetic precursor cysteine.

About IMN 1207

IMN 1207 is a cysteine-rich protein. It is the research formulation of the undenatured whey protein Immunocal(R)/HMS 90(R), a dietary natural health supplement, developed and marketed worldwide by Immunotec during the past 12 years. Immunocal(R)/HMS 90 is a precursor of the major cellular antioxidant glutathione, an element important in maintaining a strong immune system.

About Immunotec Inc.

Immunotec is engaged primarily in the development and marketing of natural health products, dietary supplements, food, vitamins and personal care products, many of which are manufactured on its behalf by third parties. Immunotec's products are distributed and sold in Canada and the United States through a network marketing system and in other countries through exclusive distributorship agreements. Immunotec's investment in this study is another manifestation of its ongoing commitment to research and development. http://www.immunotec.com.

- (x) Montreal General Hospital (McGill University teaching hospital) Montreal, Quebec, Canada

- (x) Cross Cancer Institute, Alberta Cancer Board (University of Alberta affiliate) Edmonton, Alberta, Canada

- (x) Jewish General Hospital (McGill University teaching hospital) Montreal, Quebec, Canada

- (x) Juravinski Cancer Centre (McMaster University and Hamilton Health Sciences affiliate) Hamilton, Ontario,Canada.

- (x) Allan Blair Cancer Centre (a division of Saskatchewan Cancer Foundation) Regina, Saskatchewan, Canada.

IMMUNOTEC INC.
http://www.immunotec.com

Source:

Cysteine-Rich Protein Reverses Weight Loss in Lung Cancer
Patients Receiving Chemotherapy or Radiotherapy
http://www.liebertonline.com

Cysteine-Rich Protein Prevents Weight Loss in Lung Cancer Patients: A Promising Intervention Study.
http://www.cnw.ca/

Your Key To Health

2008-05-17T23:16:00.005+07:00

Living Longer, Living Stronger
As time passes, it's become increasingly clear that glutathione and cysteine levels not only fall as we age, but the levels of these two critical substances are directly related to how well we fare as an older person. Studies have not only focussed on physical health, but also quality of life, mental functioning and sense of well-being.

Dr. Wulf Droge has for many years advocated taking advantage of this strategy. His research goes back several decades and has set the foundation for many other researchers to build upon. One such study has just recently been published in January 2008. (Curr Opin Clin Nutr Metab Care. 2008 Jan;11(1):40-4).

Australians A. Hayes and PJ Cribb have suggested that we approach strength and muscle mass in aging the same way as we approach an RSP (retirement savings plan). The more we pay attention to investing in our bodies at an earlier age, the higher the payoff when we're older.
In their words, when discussing whey protein isolate, “particularly in elderly people, simple strategies … that may improve the maintenance of skeletal muscle mass will likely result in a decrease in the overall burden of a number of diseases and improve the quality of life as we age.”Nice to be constantly reassured that we are doing the right thing!

Jimmy Gutman M.D.

Buy The Book @ Kudo.ca

Source : http://itsrandyslife.blogspot.com

Immunocal / HMS 90 Overview

2008-05-16T09:57:00.004+07:00

Immunocal bioactive whey protein (which is also called HMS90 in Canada) is a nutritional supplement manufactured by Immunotec Research LTD of Canada. Immunocal / HMS90 bioactive whey protein is a highly concentrated, highly bio-available milk serum isolate which is rich in un-denatured whey proteins (90% protein by weight), and is lactose-free and fat-free. It can be classified as both a whey protein concentrate and isolate as it is both fat free and lactose-free.

Each box of Immunocal/HMS90 is produced from 500 liters (125 gallons) of organic milk from a select closed herd of cattle which graze on natural selenium-rich grasses in the state of Idaho. The cows are not treated with hormones or antibiotics. The organic milk is shipped to a processing plant in the United States where Immunocal/HMS90 is produced without the use of high-heat pasteurization, which can damage the fragile proteins which normalize immune function and increase the body's production of its most critical antioxidant, glutathione. Immunocal is clinically proven to increase glutathione levels, normalize immune function, and is currently being studied in the treatment of AIDS, chronic fatigue syndrome, hepatitis B and C, cancer, cancer chemotherapy, and numerous autoimmune diseases.

Immunocal /HMS90 bioactive whey protein is not a prescription drug, but a natural and safe nutritional supplement produced from lactose-free whey. Immunocal has the same risks and side-effect profile as mothers' breast milk.

The product is a patented (8 Method of Use Patents, including 5 U.S. Patents) dietary supplement that is loaded with glutathione precursors that help increase glutathione production within healthy cells. Interestingly, the product paradoxically decreases glutathione levels within cancerous cells, weakening them so that they can be more easily destroyed by the body's immune system or by conventional medical interventions such as chemotherapy. The manufacturer of Immunocal / HMS90 bioactive whey protein reports that it took $10 million and 18 years of research to validate the product.

There are several other whey proteins being marketed as immune boosters, but these products universally lack clinical proof of their efficacy, and the manufacturers usually cite the clinical studies on Immunocal as proof of their benefit, a scientifically invalid practice. Immunocal ioactive whey protein shares many of the same immune promoting and enhancing properties of Mother's milk.

It has been clinically proven to increase serum and tissue glutathione levels, and its efficacy is validated by extensive research, including over 340 published scientific studies and review articles which appear in the medical literature and are available for you to examine through the following MEDLINE (National Library of medicine) link: Immunocal / HMS90 increases glutathione which is our cells' own natural antioxidant and most potent detoxifier. It has been demonstrated to enhance both healthy and deficient immune systems, and has been validated as an effective nutritional supplement by the medical community. Furthermore, Immunocal is the only non-prescription dietary supplement of it's kind to appear in the year 2000 through 2007 Physician's Desk Reference (PDR) for Prescription Drugs, although it is available without prescription! It has it's own NDC (National Drug Control) number, and is reimbursable under Medicaid, Medicare, and by private insurance in many states.

"About Natural Health Product Regulation in Canada"

"All natural health products require a product licence before they can be sold in Canada. Obtaining a licence will require submitting detailed information on the product to Health Canada, including: medicinal ingredients, source, potency, non-medicinal ingredients and recommended use.

Once a product has been assessed and granted market authorization by Health Canada, the product label will bear an eight digit product licence number preceded by the distinct letters NPN, or, in the case of a homeopathic medicine, by the letters DIN-HM. This number on the label will inform consumers that the product has been reviewed and approved by Health Canada for safety and efficacy."

http://www.hc-sc.gc.ca/dhp-mps/prodnatur/about-apropos/index_e.html

"The consumer will benefit from having more information available to make informed decisions, and by having regulatory approvals that increase their confidence in the safety and efficacy of NHPs, possibly resulting in an increase in consumer self-medication, and a possible decrease in medical problems and associated costs.

Practitioners will benefit from the added confidence in the safety and efficacy of NHPs, and will be better able to make product recommendations to their patients due to the increased information on product labels. Consumer confidence will also be enhanced by government review of products in a pre-market system, which assures them that what is on the label is what is in the bottle, and that health claims are supported by appropriate standards of evidence."
"Canadian manufacturers and distributors of NHPs want to put more, rather than less, information on labels, as long as the information is deemed reasonable by the industry."
"In summary, from an overall perspective, it is expected that there will be significant benefit to consumers from the new regulatory framework.

Many studies have indicated that there are societal net benefits from informed and effective self-care, including maintenance of good health. By allowing more information on labels regarding health claims associated with NHPs, and by establishing a regulatory framework that increases consumer confidence in NHPs, the new regulatory regime may lower the cost of maintaining one's health or increase the healthiness of consumers.
Complete labelling also provides the consumer with full disclosure of NMIs and any warnings or contra-indications, thereby increasing consumers' knowledge and awareness regarding sensitivities, allergens, and interactions.

As a direct result, negative reactions to certain substances could be reduced, and the corresponding need for medical attention decreased. As well, as indicated earlier, the consumer benefits from having more information available to make informed decisions, and regulatory approvals that increase their confidence in the safety and efficacy of NHPs. Increased consumer confidence will lead to stability or an increase in sales of these products from an industry perspective. Industry has indicated that while it recognizes there will be incremental costs associated with regulation specific to NHPs, it also values increased consumer confidence in these products, and overall benefits to consumers regarding informed choice.

Health Canada has considered the benefits and costs associated with the introduction of these Regulations from the perspective of all stakeholders including industry and consumers, and concluded that the benefits outweigh the costs of adopting this regulatory framework."

http://canadagazette.gc.ca/partII/2003/20030618/html/sor196-e.html

"Immunotec Research Ltd. represented by Comprehensive Health Management CorporationAfter 18 years of research and development Immunotec Research Ltd. is proud to introduce IMMUNOCAL, a powerful and unique nutraceutical food supplement."

"IMMUNOCAL is patented as a method of raising and sustaining tissue glutathione levels, as a means of improving active humoral immune response and as a method of treatment for HIV seropositive individuals and a treatment for cancer."

"Immunocal is an undenatured bioactive whey protein loaded with Glutathione precursors."

"Immunocal has been evaluated by the CDC to stop and retard the replication of the AIDS virus. It is FDA approved and is reimbursable under Medicare/Medicaid."

http://www.dshs.state.tx.us/hivstd/conference/1999/support.shtm

Source : http://itsrandyslife.blogspot.com

Health Canada Approves Health Claim for HMS 90 / IMMUNOCAL

2008-05-15T20:36:00.003+07:00

MONTREAL, Nov. 13 /CNW Telbec/ - Immunotec Inc. (TSX-V IMM) announces that it has received regulatory approval from Health Canada to market HMS 90 / IMMUNOCAL with the following health claim: "a natural source of the glutathione precursor cysteine for the maintenance of a strong immune system."

The Natural Health Products Directorate (NHPD) is Health Canada's division responsible for the evaluation of the safety, efficacy and quality of natural health products. It has issued a Natural Product Number (NPN) for HMS 90 / IMMUNOCAL based on the credibility, strength and quality of evidence provided to support the claim.

Immunotec strongly supports the implementation of the Natural Health Products Regulation. President and Chief Executive Officer Jim Northrop notes: "The imposition of high standards to ensure the quality, safety and efficacy of natural products supports Immunotec's commitment to excellence in product development and manufacturing. The issuance of this NPN reinforces to consumers and Distributors alike that superb scientific evidence is the foundation for HMS 90 / IMMUNOCAL. This fact, along with the important associated health claim could have a significant impact on Immunotec's business growth."

Senior Vice-President, Research & Development, Dr. Wulf Droge, is extremely pleased about this regulatory approval. "What consumers have known for quite some time has now been formally recognized by the NHPD: the health benefits of Immunotec's lead product HMS 90 / IMMUNOCAL for the immune system are based on solid science."

Natural Health Products must be manufactured, packaged, and labelled in Health Canada-approved facilities according to current Good Manufacturing Practices to ensure optimal quality of the finished goods. The evaluation of the efficacy of a specific product allows consumers to make an informed choice when including natural health products in their wellness regimes.

About Immunotec Immunotec operates out of a 37,000 square foot facility located in Vaudreuil-Dorion, Quebec, Canada as well as a distribution centre located in Swanton, Vermont, USA. Immunotec is engaged primarily in the development and marketing of natural health products, dietary supplements, food, vitamins and personal care products, many of which are manufactured on its behalf by third parties. Immunotec's products are distributed and sold in Canada and the United States through a network marketing system and in other countries under exclusive distributorship agreements.

%SEDAR: 00011993EF -0- 11/13/2007 /For further information: Media contact: Richard Patte, Executive Vice-President, (450) 510-4445, rpatte(at)immunotec.com/ (IMM.) CO: IMMUNOTEC INC.

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Debec IN: MTC HEA BIO SU: PDT -30- CNW 12:19e 13-NOV-07

Source : http://www.canadianbusiness.com

Immunocal/HMS90 Questions and Answers

2008-05-14T09:14:00.003+07:00

Q. What is Immunocal®? What is HMS-90®?

A. Immunocal® is known as HMS90® in Canada. This unique product is manufactured by Immunotec Research in Montreal, Canada. It is not a prescription drug, but a powerful and patented un-denatured and highly bioactive whey protein dietary supplement that is loaded with glutathione precursors.

Immunocal® took $10 million and 18 years of research to perfect. It is unique in the nutritional field as it is covered by 10 ‘Method of Use’ patents worldwide: 5 in the US, 3 in Canada and 2 in Australia. Immunocal® is a highly concentrated milk serum isolate which is high in protein (90% protein by weight) and is lactose-free and fat-free. Immunocal® shares many of the same immune promoting and enhancing properties of Mother's milk. Immunocal® has been clinically proven to increase serum and tissue glutathione levels, and its efficacy is validated by extensive research, including over 450 that appear in the medical literature. These scientific papers can be examined through MEDLINE (the US National Library of Medicine). Immunocal® increases glutathione which is your cells' own natural antioxidant and most potent detoxifier. Immunocal® has been demonstrated to enhance both healthy and deficient immune systems, and is validated as an effective nutritional supplement by the medical community. Immunocal® has its own NDC (National Drug Control) number, and is reimbursable under Medicaid, Medicare, and by private insurance in many states.

Q. Can children take Immunocal?

A. Yes they certainly can. There is no problem with side effects or worry about conflicts with medication. Children should be given 11/4 teaspoon of Immunocal for every 3 lbs of body weight.

Q. What is the difference between Immunocal and other whey proteins?

A. Immunocal has been shown to differ from other whey proteins in its effect upon the immune system. Specifically, scientific studies on other whey proteins have not shown the same immune stimulating effects that are seen with Immunocal®. Immunocal has been extensively studied in the clinical literature. Comparing the bioactive ingredients in Immunocal to those in other whey proteins clearly shows the superiority of Immunocal®. Immunocal is a bioactive dietary supplement that is supported by eighteen years of research through rigorous clinical trials that have been published in peer review journals. These studies, performed in world-renowned medical and scientific institutions, attest to the efficacy of Immunocal. Immunocal studies have shown that Immunocal not only increases intracellular levels of GSH (glutathione or glutathione precursors) following ingestion, but also significantly builds up the stores of these substances inside the cells. This beneficial effect lasts for considerable periods of time after ingestion of Immunocal.

Q. What is the product's bioactivity dependent upon?

A. Concentrations of 3 bioactive and thermo labile (easily damaged by heat) proteins that are contained in the milk serum: serum albumin, alpha lactalbumin and lactoferrin. Because these compounds can be damaged by heat (in excess of 140 degrees F) or excessive mechanical agitation, Immunocal® must not be cooked, heated, or placed in a steel-bladed blender. For these reasons, and to preserve the bioactivity of its serum albumin, alpha lactalbumin and lactoferrin, Immunocal® has not been exposed to standard high-temperature Pasteurization. Rather, it has been bio-filtered to remove bacteria, and subjected to a patented process of low-temperature purification procedures to ensure its safety and purity.

Q. If a different manufacturer of whey protein supplements was able to duplicate our technology, could they make the same claims?

A. No. The power of our patents is not in manufacturing. Immunocal patents (presently there are ten patents on Immunocal®: 5 US patents, 3 Canadian and 2 Australian patents relate to the METHOD OF USE. That is, no other whey protein can state: "clinically PROVEN to stimulate the immune system", and "significantly raises glutathione levels". Additionally, although there are dozens of companies producing DENATURED (high-heat Pasteurized) whey proteins (primarily for use as a protein source in body-building), there currently is no company manufacturing an UNDENATURED whey protein product similar to Immunocal. Over 450 clinical studies and medical reviews appear in the clinical literature which specifically involved Immunocal®, and not other whey proteins. Accept no imitations.

Q. What exactly is glutathione (GSH) and how is it important?

A. Glutathione is the master antioxidant of the body. Without glutathione, we would die. The replenishment of the glutathione levels within the lymphocytes (also called leukocytes or white blood cells) increases the intensity of the immune response. The increase in glutathione levels also results in the proliferation of lymphocytes that act as scavengers, and helps to combat infections. Selenium is a structural component of, and a co-factor for the antioxidant enzyme glutathione peroxidase. For this reason, supplementation with selenium can modestly increase glutathione levels in persons who are selenium deficient. Glutathione is a tri-peptide of the amino acids cysteine, glycine, and glutamic acid. Tissue glutathione levels increase when cystine levels increase within the cell. This is why cystine is critical in the production of glutathione. Prior to the development of Immunocal, no effective way was known to safely and significantly increase cystine levels in the cell over long periods of time. A deficiency of glutathione can cause haemolysis (the destruction of red blood cells resulting in severe anaemia) and numerous diseases of oxidative stress. Glutathione is essential in intermediary metabolism as a donor of sulfhydryl groups that are essential for the detoxification of the liver. The antioxidant enzyme glutathione peroxidase functions in the process of elimination of wastes from the body. Glutathione works within the liver, lungs, colon, kidneys, and skin in the process of removing toxic cellular metabolic wastes.

Q. What is the difference between products or pills that people use as supplements that are labelled as "glutathione" or "cystine"?

A. Glutathione must be produced within the cells (intra-cellularly). Clinical and laboratory studies demonstrate that oral glutathione is NOT absorbed but will be eliminated by the liver through the bile before ever reaching the systemic circulation (blood stream). Several studies have suggested that supplementing with oral glutathione may actually do the reverse and depress cellular and blood levels of glutathione. Injectable glutathione also has limited benefits. It is unstable in the blood stream. By the time it reaches the cell, much of it has been degraded, and much of the remaining glutathione cannot effectively pass through the cell membrane. Cystine is not well absorbed when taken by mouth. Clinical studies have demonstrated that oral cystine supplementation (NAC or N Acetyl LCysteine) is not effective in increasing cystine levels within the cell, and also has not been associated with significant increases in glutathione levels within the cell. The three bioactive proteins supplied by Immunocal constitute a "natural delivery system" from these cystine precursors to the cell (in order to facilitate clinically and statistically significant increases in glutathione levels in BOTH the extracellular serum and intracellular tissues). Because Immunocal® provides the building blocks for cystine, and these building blocks for cystine are easily transported inside the cell where they can be quickly synthesized into glutathione, Immunocal® is therefore ideally suited to increase glutathione levels within the cell.

Q. What is the difference between NAC (N Acetyl L-Cysteine) and Immunocal/HMS90®?

A. N Acetyl L-Cysteine (NAC) is an Antioxidant Drug, which has been demonstrated to facilitate the SHORT TERM cellular detoxification of alcohol, tobacco smoke, acetaminophen [Tylenol®] poisoning and environmental pollutants in several in-vitro (in a test-tube) studies. When Cystine is heated, molecular bonds are cleaved and it becomes Cysteine. Cysteine is beneficial if it is produced INSIDE the cell, but is mildly toxic if it is produced outside the cell. NAC does not travel well in the blood stream, and doesn't reach the cells (to be used to synthesize glutathione and Glutamic acid). NAC supplementation over long periods has been associated with modest increases in serum glutathione, but has not proven particularly useful in the treatment of chronic, long-term intracellular glutathione deficiencies. Furthermore, therapeutic levels of NAC are relatively toxic and have been associated with significant side effects. At therapeutic doses, oral NAC supplementation has been associated with cerebral symptoms: nausea, blurred vision, and vomiting. Immunocal provides the precursors for the manufacture of intra-cellular cystine, and effectively delivers these to the cell. For this reason, Immunocal supplementation has been associated with sustained and significant increases of cellular glutathione, and is virtually devoid of troublesome side effects. Immunocal® has the same side-effect profile as mothers' milk.

Q. What is the difference between bovine colostrum and Immunocal®?

A. The proteins in colostrum have almost no cystine content. Cystine is critically essential to the immune system. Although growth factors present in colostrum (including IGF-1, or Insulin-like growth Factor-1 which is effective in promoting muscle growth) are not affected by stomach acid, research published by one manufacturer of Colostrum (Vital Health News, Winter 1998, page 7) demonstrated that "the effectiveness of the immune factors present in colostrum is lowered by stomach acid." Although the immune enhancing factors found in colostrum are often "preferable to single isolated immune components" (such as interferon, which is more likely to cause troublesome side effects), colostrum has NOT been demonstrated to be superior to isolated undenatured whey proteins such as Immunocal®. Colostrum (which is produced by the mammary glands during the first 26 hours following birth) is primarily composed of immunoglobulin and some lactoferrin. According to both laboratory experiments and clinical trials conducted in Germany, although colostrum supplementation was associated with mild increases in immune function in some patients, these increases were not statistically significant. A postulated mechanism of the action of colostrum is the inter-species transfer of immune factors, however this has NOT been clinically proven. Most of the data supporting the effectiveness of colostrum is anecdotal (consisting mostly of personal testimonies rather than clinical studies). Since the primary mechanism of action on the immune system is via stimulation of the synthesis (production) of glutathione, the near absence of glutathione precursors in the immunoglobulin fraction (from the colostrum) may explain its relative lack of effect. Conversely, Immunocal contains substantial amounts of thermolabile (heat-sensitive) proteins which are rich in cystine and glutamylcystine (known precursors of glutathione), and the effectiveness of Immunocal has been demonstrated in numerous human clinical trials which found statistically significant increases in glutathione and indices of immune function (such as CD4:CD8 ratios). Colostrum might be beneficial as an adjunctive (add-on) therapy to Immunocal®, but the clinical data is significantly more convincing for Immunocal/HMS90®.

Q. What are some additional benefits of un-denatured whey proteins?

A. Immunocal® has been clinically demonstrated to increase exercise capacity by 13 percent (Lands et al., 1999), and may be useful as a supplement for competitive athletes. Wattanabe et al. (Japan) conducted a clinical study with Immunocal to evaluate increases in GSH among patients with Hepatitis B and C, and found that these viruses are vulnerable to glutathione. In-vitro studies in Japan also showed that whey could stimulate the bone cell (osteoblasts) to produce more bone, hence increasing bone density and reducing the risk of osteoporosis. Lactalbumin from whey protein has been demonstrated to kill breast cancer cells in-vitro. Glutathione (from whey protein) lowers serum cholesterol by stimulating bile synthesis in the liver. In addition, glutathione is a powerful antioxidant that will prevent lipid peroxidation (a sign of free radical activity). Lipid peroxidation is implicated in arteriosclerosis (hardening of the arteries), stroke and coronary artery disease.

Q. How does the manufacturing of our product differ from other whey proteins?

A. In the manufacturing of other whey proteins several things occur: in the process of heating and Pasteurization, critical bonds holding the cystine together get broken down ("denatured", meaning they lose their original nature--similar to the denaturing and irreversible changing of liquid egg white by the heating process involved in frying an egg). The exact type of proteins that serve to increase tissue and serum glutathione most effectively are lost or diminished. The researchers at Immunotec (the manufacturers of Immunocal®) have developed a process by which these delicate proteins remain intact in their natural form to serve us most effectively.

Q. What is the theoretical mechanism of action of GLUTATHIONE (GSH) in Cancer and Immune dysfunction?

A. Natural killer (Immune) cells may become glutathione-depleted over time, and their immune response weakens. Immunocal raises glutathione levels and strengthens the immune system to fight cancer, viruses, bacteria, etc. For those patients receiving traditional medical therapy for their cancers, Immunocal supplies lactalbumin and has been clinically proven to raise glutathione levels. Glutathione and lactalbumin (a component of Immunocal®) have been associated with the strengthening of healthy cells and (paradoxically) the weakening of cancerous cells. In research conducted by C. Svanborg et al, lactalbumin was associated with apoptosis (or the programmed death) of breast cancer cells. Glutathione has been scientifically demonstrated to decrease cancerous cells' resistance to chemotherapeutic drugs, while protecting healthy cells. This should allow a patient to respond better to chemotherapy with fewer side effects.

Q. What are the diseases or conditions that have been associated with low glutathione levels?

A. There are over 100 diseases and conditions associated with low glutathione levels. Most of the degenerative diseases of aging and the autoimmune diseases have been studied and linked to low GSH levels including: Acetaminophen poisoning, ADD, Addison's disease, aging, AIDS, alopecia areata, ALS, Alzheimer's' disease, anaemia (haemolytic), ankylosing spondylitis, arteriosclerosis (hardening of the arteries), arthritis (rheumatoid), asthma, autism, autoimmune disease, burns, cacexia, cancer, candida infection, cardiomyopathy (idiopathic), Chronic Fatigue Syndrome, colitis, coronary artery disease, cystic fibrosis, diabetes, Crohn's disease, eczema, emphysema, Epstein Barr Viral (EBV) syndrome, fibromyalgia, free radical overload, Graves' disease, hepatic dysfunction (liver disease), hepatitis B, hepatitis C, hypercholesterolemia (high blood cholesterol), herpes, infections (viral, bacterial and fungal), inflammatory bowel diseases (IBD), lupus, macular degeneration (diabetic and age-related macular degeneration), malnutrition, Meniere's disease, multiple sclerosis, Myasthenia Gravis, neurodegenerative diseases, nutritional disorders, Parkinson's disease, primary biliary cirrhosis, progeria, psoriasis, rheumatic fever, sarcoidosis, scleroderma, shingles, stroke, surgery, toxic poisoning, trauma, vasculitis, vitiligo, Wegener's Granulomatosis, to name a few.

Q. Has therapy to increase glutathione levels been effective in treating the diseases or conditions that have been associated with low glutathione levels?

A. Yes. There have been many thousands of research studies proving that raising glutathione levels is an effective treatment in dozens of diseases and conditions. Of course, prevention is always amore desirable path. Immunocal/HMS90 has been proven to raise and maintain healthy levels of glutathione.

Q. Can a person who is lactose intolerant take Immunocal/HMS90®?

A. Yes, Immunocal® has less than 1% lactose which should not cause any ill effect even in the most severe case of lactose intolerance.

Q. Are there any interactions known between supplements such as coenzyme Q-10, antioxidant vitamins, or herbs and Immunocal/HMS90®?

A. No, there are no known potential or reported interactions between Immunocal and nutritional supplements. In fact, Immunocal increases glutathione levels that help to improve the action of antioxidant vitamins (which are less effective if your glutathione levels are impaired). For this reason, mega-doses of antioxidant vitamins (i.e. doses in excess of 10 times the RDA of these vitamins) are not required if you are supplementing with Immunocal®. As we age, our glutathione levels fall precipitously like a downhill ski-slope. Low levels of glutathione are associated with a host of degenerative diseases, and critically low levels of serum and tissue glutathione often predict that death is imminent. Supplementation with Immunocal/HMS90® helps restore these precious glutathione levels, and assists the supplemental vitamins you may be taking to work more effectively.

Q. Are there any interactions known between prescription medications and Immunocal/HMS90®?

A. No, there are no known interactions between Immunocal and prescription drugs. Immunocal is composed of the same basic proteins that are found in human breast milk, and should be considered to be as safe to take as mothers' breast milk. Furthermore, Immunocal® is 90% protein, and is one of the best sources of highly absorbable protein on the planet. Patients taking immunosuppressant drugs such as Cyclosporin® after such treatments as organ transplants should consult their physician before taking Immunocal®.

Q. Are there any side effects associated with Immunocal/HMS90®?

A. Immunocal® increases serum and tissue glutathione levels. When liver tissue glutathione levels rise, the liver is able to more effectively detoxify the body (which is a beneficial function of Immunocal®). Some patients (especially those who have been exposed to high levels of environmental toxins) may have a mild temporary reaction to these mobilized toxins as the liver is removing them from storage in body fat. Typically, reducing the dose of Immunocal® will allow these temporary side effects quickly disappear. Immunocal is composed of the same basic proteins that are found in human breast milk, and has the same side effect profile as mothers' breast milk. Because Immunocal® is a milk protein, persons who are mildly allergic to milk proteins may experience minor gastric distress from Immunocal®. This gastric distress usually disappears if you reduce the dose of Immunocal®. Persons with serious milk-protein allergies should not take Immunocal®.

Q. Can you overdose Immunocal/HMS90®? Is there any potential for toxicity if you take too much?

A. Your greatest risk is wasting your money if you take "too much" Immunocal®. Clinical data seems to indicate there is limited benefit from exceeding 30 grams (3 packets) per day of Immunocal®. Because our cells have an innate mechanism of "feed-back inhibition" with respect to the glutathione synthesis precursors (building blocks) provided by Immunocal®, there is no potential for making "too much glutathione" within the cell if large quantities of Immunocal® are consumed. Immunocal® supplementation will result in establishment of normal glutathione levels, (NOT excessive glutathione levels) within the cell. Excess Immunocal/HMS90® would be metabolized as protein (Immunocal® is an excellent source of protein, containing 90% protein by dry weight).

Q. Because Immunocal/HMS90® is 90% protein, is it contraindicated in patients on renal dialysis who must limit protein intake?

A. No, Immunocal/HMS90® is not contraindicated in these patients. Although we suggest that you consult your personal physician with individual medical questions such as these, there is no reason to believe that Immunocal/HMS90® would be anything but helpful for these patients. Immunocal® is one of the most easily digested and most easily absorbed forms of protein in the diet. Its Protein Efficiency Ratio (PER: a mark of the quality of a protein) is extremely high, and in conditions such as renal failure where protein intake must be limited, it is most prudent to consume the highest quality proteins such as whey proteins and egg white proteins, versus lower quality proteins that produce more problematic metabolic waste by-products and residues.

Q. Is Immunocal/HMS90® contraindicated in Celiac Sprue disease?

A. These patients are usually instructed not to ingest wheat or gluten. There is no wheat, or gluten in Immunocal. Furthermore, Immunocal® is lactose-free. There is no reason to believe that Immunocal® would be detrimental in patients with Celiac Sprue Disease.

Q. Who should not take the product?

A. People with an allergy specifically to milk protein, (which is very rare). NOTE: Please understand that lactose intolerance is NOT a milk allergy. Also, anyone who has had an organ transplant and is receiving immunosuppressant therapy should not take Immunocal. The immune system needs to be suppressed in order to prevent organ rejection.

Q. What are some of the critical ingredients in a daily amount of Immunocal/HMS90® (1 pouch)?

A. 9 grams or 90% Protein, 0 mg Fat, less than 1% Lactose, 60 mg of Calcium, 4 micrograms of Selenium, 30 Mg of Potassium, 4 mg of Iron, and approximately 40 Calories.

Q. What is the recommended dose for taking Immunocal/HMS90®?

A. Check with your physician or health care professional. If you do not have a documented glutathione deficiency and are taking Immunocal for good health, one pack per day is the usual maintenance dose. Generally, most studies conducted using Immunocal in patients with glutathione deficiencies used at least 20 grams per day (2 pouches), and some studies showed increased effectiveness using up to 30 grams (3 pouches) per day.

Q. What is the difference in taking Immunocal/HMS90® as opposed to taking other antioxidants?

A. Vitamin E and C are important antioxidants, and you should consider these important supplements in your diet. Immunocal® is not an antioxidant per se, but provides the building blocks for the synthesis of the principle intra-cellular antioxidant, glutathione. Glutathione is the most potent cellular antioxidant known to man, and is hundreds of times more potent than vitamin C or vitamin E. For this reason, glutathione has been called the "Super Antioxidant".

By raising the glutathione level within our bodies we provide for the optimum functioning of other lesser antioxidants such as vitamins C and E. More importantly, glutathione serves as a detoxifying agent for multiple toxins that we encounter on a daily basis through the environment and the medications we take. Glutathione has been demonstrated to act as an effective protectant against ultraviolet radiation, which is important in view of the continued loss of the ozone layer.

Q. What is the best way to mix Immunocal/HMS90®?

A. Because Immunocal is a very fine and delicate powder, we recommend mixing it with any juice or liquid that is not above lukewarm (110 degrees F), and NEVER above 120 degrees F. First, mix the packet with approx. 1 tablespoon of the liquid you have chosen, to form a paste. Then pour the liquid to fill your glass. Allow it to sit for a few minutes, stir, and enjoy. Immunocal can also be mixed in applesauce, yoghurt, or sprinkled over cereal without any particular mixing procedure. The product should not be mixed at high speed in a blender (mechanical mixing damages the milk proteins). If you are making a breakfast “smoothie”, put all the ingredients except the Immunocal/HMS90® into the blender, mix at high speed, then reduce the blender speed to ‘Fold’ or ‘Low’ before adding the Immunocal/HMS90®. You can mix Immunocal by hand, whisk, covered shaker cup or inexpensive "vortex-mixer". We will ship you a portable, battery-operated vortex-mixer FREE with your first shipment of Immunocal® on the Immunocare (Autoship) program (when you sign up using your credit card to receive monthly shipments of 1 box of Immunocal® or more), or when you purchase a business-builder “Action Pack".

Q. When is the best time of day to take Immunocal/HMS90®?

A. There is no ‘best time’ to take this product. Because foods such as yoghurt and orange juice are generally morning foods, most people take Immunocal/HMS90® with breakfast. There is nothing wrong with taking it with lunch or dinner or as a midday snack. It will be better absorbed if taken on a relatively empty stomach, i.e. not with or after a heavy meal.

Source : File Immunocal.pdf

Patents Make a Difference

2008-05-13T20:34:00.004+07:00

Some products on the market today promote themselves using the research of other companies. It is easy for a company to get a Composition Patent. Basically, submit your "recipe" for your product and you can claim that your product is patented. But what does that really mean to me and you?

Method of Use patents on the other hand, are Very Different. In order to get this type of patent you need to complete double blind studies (using your product), peer reviewed papers, needs to be renewed annually and on an on.

Immunocal has 10 Method of Use patents.

To see the U.S. and Canadian patents, click on the links below.

United States: 5,888,552, 5,451,412, 5,230,902, 5,456,924, 5,290,571, 5,846,939

Canada: 2,142,277 2,090,186 1,333,471 1,338,682

Source : www.immunocal.com

Presentation about Immunocal on FDA website

2008-05-13T08:57:00.003+07:00

The product validation includes a presentation from the FDA website. It references Undenatured Whey Protein Isolate (Immunocal).

Have a look at the presentation.

Source : http://gshthemasterantioxidant.blogspot.com

Researchers

2008-05-12T09:26:00.013+07:00

Discoverer of Immunocal®

Educated at the University of Turin and the University of Genoa in his native Italy, Gustavo Bounous’ distinguished career in medical research began as a Research Fellow in surgery at the Indiana Medical Center, Indianapolis. In 1963, he moved to Canada and commenced an academic career that led him to become Professor of Surgery, firstly at the University of Sherbrooke (1973-1985), then at McGill University (1985-1993).

Dr. Bounous was awarded the 1965 medal of the Royal College of Physicians and Surgeons of Canada. He pioneered the use of elemental diets in the prophylaxis and treatment of intestinal lesions associated with shock, intestinal ischemia, radiation, cancer chemotherapy and Crohn’s disease.

In 1968, he was named Career Investigator of the Medical Research Council, an award that was reconfirmed until 1993, the year of his retirement from McGill University. In 1978, Dr. Bounous initiated a novel research program to search for a dietary protein source that would boost the immune system, in conjunction with a colleague from the McGill University Faculty of Medicine. Studies led to the discovery of an undenatured serum milk concentrate that sustains normal glutathione levels and promotes immune enhancing activity. Subsequent identification of the active ingredients present in this protein mixture, brought on in 1993, the production of a high-quality bioactive material given the name and trademark Immunocal®.

Co-Discoverer of Immunocal®

Patricia Kongshavn received her Honors Degree in Natural Sciences as a Major Scholar at Cambridge University, and completed her doctorate in Immunology at McGill University after immigrating to Canada. She subsequently joined the Faculty of Medicine at McGill University and held appointments in the Departments of Physiology and Medicine, becoming Full Professor in 1986. Her research was funded by independent grants to her from the Medical Research Council of Canada, the National Cancer Institute of Canada and the National Institutes of Health in the United States.

Her main research was concerned with increasing basic knowledge of the immune system, with a focus on cellular immunology, host/parasite interactions and the genetics of natural resistance.

In the mid-1970’s she began collaboration initiated by Dr Gustavo Bounous to research the influence of various dietary proteins on immune responsiveness. They published their first paper on this research in 1978 and continued their collaboration until 1989, during which period they co-authored 14 papers. This work led to the discovery of an undenatured whey protein concentrate that regulated glutathione levels and promoted immune enhancing activity. This led ultimately to the production of a high quality bioactive nutraceutical: IMMUNOCAL®.

Dr. Konghavn retired from McGill to relocate to the West in 1990 and currently acts as a consultant to NuMedTec.

Source : www.immunocal.com

The Science of Glutathione2

2008-05-11T09:18:00.008+07:00

A New Outlook on Life's Health Challenges

Let's face it, most of us live a fast-paced lifestyle that is very demanding on our health. The habit of reacting only once the body breaks down is giving way to the realization that prevention can be the best medicine.

Glutathione is emerging as one of the keys to the health puzzle. It was the discovery of glutathione's importance in optimizing your body's first line of defense - your immune system - that led to the development of a whey product that raises intracellular glutathione.

Glutathione: The Next Household Word
You may or may not have heard of glutathione, even though over tens of thousands of medical articles have highlighted its importance. Optimizing glutathione levels will shortly join the list of factors known by everyone to have an impact on our health and well-being, along with vitamin supplementation and cholesterol regulation.

Glutathione is a small protein produced naturally in every cell of our body. It is made up of three protein building blocks, called amino acids. These are glutamic acid, cysteine and glycine. The cysteine amino acid contains a sulfur group responsible for the chemical properties of the whole glutathione protein.

Glutathione: An Essential Health AID
There are three major roles of glutathione in the body: Antioxidant, Immune booster, and Detoxifier. Even cells in the healthiest of individuals constantly need to replenish their glutathione supply.

The Master Antioxidant (AID)
Antioxidants participate directly in the destruction of reactive oxygen compounds called free radicals. These by-products of a cell's normal function can't be avoided, but exposure to ultraviolet radiation from the sun or other sources promotes their emergence. Free radicals have been linked to muscle fatigue during exercise and aging.

For this reason, the body is equipped with a variety of antioxidants. Vitamins C and E are natural antioxidants but do not occur naturally in the body. These and other antioxidants actually depend on glutathione to function properly, which is why glutathione is called "the Master Antioxidant".

Food For the Immune System (AID)
Glutathione helps build your immune system's resistance and improve your chances of staying healthy.

Lymphocytes are cells of your immune system. Glutathione is essential for lymphocytes to increase in number, produce antibodies, and function efficiently.

A Natural Detoxifier (AID)
Our food and water sources are becoming increasingly contaminated with chemicals, as is the air that we breathe. Supplemental detoxifiers such as glutathione help to counter the effects of the toxins we inhale and ingest.

By physically binding to toxic compounds in cells, glutathione helps make them soluble - and harmless. The body can then eliminate these disarmed toxins in the bile and urine.

Raise Glutathione Levels But How?
The fact is, you can't ingest glutathione to feed it to your cells. Glutathione must be manufactured within your cells. What you can do is help this natural process by giving your body the glutathione building blocks it needs. The limiting factor in your daily intake of building blocks is the amino acid cysteine.

Cysteine, traveling alone as an amino acid through our digestive system, is poorly absorbed and very little of it will actually make the trip from our mouths to our cells. Luckily, when cysteine molecules bind to each other to travel in pairs, they can survive this process. They do this by forming a bond between sulfur molecules. These bonded cysteine amino acids are then called 'cystine'. Although this sulfur bond is resistant to the digestive process, it is easily broken if submitted to heat or mechanical stress.

Immuncal's Unique Manufacturing Process
Before Dr. Bounous and his colleagues devised the technique used to produce Immunocal, the scientific community was unsuccessful at producing a supplement rich in active bonded cysteine.

Immunocal is a highly purified protein powder isolated from whey (milk serum). Immunocal's secret lies in its proprietary manufacturing process that guarantees:

*The most natural of products isolated in the most natural of conditions.
*A protein source that remains active, which is accomplished by maintaining the fragile, precious bond between cysteine amino acids.
*An even distribution of active protein throughout the product, for the same efficacy inevery serving.

Raise Glutathione Levels - Safely and Naturally
There are other synthetic ways in which glutathione levels may be raised. However, the high level of side effects limits their long-term use. In contrast, Immunocal is just as effective and has no known side effects when used as directed. It contains natural proteins isolated from milk, but a negligible amount of lactose; therefore, even lactose - intolerant individuals can use it safely.

Immunocal: Feeding Bonded Cysteine to Cells
Numerous clinical studies have been performed, using the highest standard of scientific design, to prove Immunocal's efficacy and reliability. In one such study, Immunocal was proven to raise glutathione levels by 35.5% in lymphocytes.

What's more, testimonial evidence from thousands of satisfied customers in a dozen countries confirms what science was able to prove: Immunocal works!

*The Effect of Supplementation with a Cysteine Donor on Muscular Performance
Published in the Journal of Applied Physiology, 87: 1381-1385, 1999
by LC Lands, MD, PhD, VL Grey, PhD, AA Smountas, BSc*
*Division of Respiratory Medicine, Department of Pediatrics, Department of
Biochemistry, McGill University Health Centre - Montreal Children's Hospital,
Montreal, Quebec, Canada

This study was conducted in healthy adults for 3 months using the highest standard of scientific design (peer-reviewed, double-blind, randomized, prospective and placebo-controlled study) to ensure validity of the results. Statistical calculations were performed to analyze the results.

Praise and Recognition From the Past and Present
Immunotec Research Ltd., is a research organization first and foremost and as such, is dedicated to marketing products that have received the highest approval from the scientific community. Immunocal is no exception.

Scientists have shown their support for Immunocal in many ways through the years, from its inception to its introduction to the North American market in 1996:

*Immunocal is patent-protected worldwide
*Immunocal is also listed in the U.S. Physicians' Desk Reference and the Pharmacist's Red Book
*Immunocal joins a select group of nutritional products qualifying for reimbursement coverage under Medicare/Medicaid in the United States

Source : http://www.squidoo.com

The Science of Glutathione1

2008-05-09T09:06:00.014+07:00

Glutathione (GSH) is a small molecule found in almost every cell. It cannot enter most cells directly and therefore must be made inside the cell, from its three constituent amino acids: glycine, glutamate and cysteine. The rate at which glutathione can be made depends on the availability of cysteine, which is relatively scarce in foodstuffs. Furthermore, the cysteine molecule has a sulfur-containing portion which gives the whole glutathione molecules its “biochemical activity”, i.e. Its ability to carry out the following vitally important functions:

Firstly, glutathione is the major antioxidant produced by the cell, protecting it from ‘free radicals’ (oxygen radicals, oxyradicals). These Highly reactive substances, if left unchecked, will damage or destroy key cell components (e.g. Membranes, DNA) in microseconds. Oxyradicals are generated in many thousand mitochondria located inside each cell, where nutrients like glucose are burnt using oxygen to make energy. (Mitochondria can be thought of as the batteries that provide the power for the cells to operate). Oxyradicals also come from pollutants , from UV radiation and as other sources. In addition, glutathione recycles other well know antioxidants such as vitamin C and vitamin E, keeping them in their active state.

Secondly, glutathione is a very important detoxifying agent, enabling the body to get rid of undesirable toxins and pollutants. It forms a soluble compound with the toxin that can then be excreted through the urine or the gut. The liver and kidneys contain high levels of glutathione as they have the greatest exposure to toxins. The lungs are also rich in glutathione partly for the same reason. Many cancer producing chemicals, heavy metals, drug metabolites etc. Are disposed of in this way.

Thirdly, glutathione plays a crucial role in maintaining the normal balance between oxidation and anti-oxidation. This, in turn, regulates many of the cell’s vital functions, such as the synthesis and repair of DNA, the synthesis of proteins and the activation of regulation of enzymes.

Fourthly, glutathione is required in may of the intricate steps needed to carry out an immune response. For example, it is needed for the lynphocytes to multiply in order to develop a strong immune response, and for ‘killer’ lymphocytes to be able to kill undesirable cells such as cancer cells or virally infected cells.

The importance of glutathione cannot be overstated. It has multiple roles as indicated and, indeed, as one examines each systems or organ more closely, the necessity for glutathione becomes increasingly evident. Glutathione values decline with age and higher values in older people are seen to correlate with better health, underscoring the importance of this remarkable substance for maintaining a healthy, well-functioning body.

1. by Patricia A.L. Kongshavn, Ph.D.
Former Professor: Department of Medicine
McGill University, Montreal, Canada

Reference - Lomaestro B. Malone M. Glutathione Health and disease: Pharmacotherapeutic Issue, Ann Phamacother 29: 1263-73.1995.

Source : http://www.gsh-booster.com